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- 產(chǎn)品名稱：Recombinant Human BD-1, 47a.a.
- 產(chǎn)品型號(hào)：
- 產(chǎn)品展商：XYbscience
- 產(chǎn)品文檔：無相關(guān)文檔
簡(jiǎn)單介紹
Recombinant Human BD-1, 47a.a.由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn)，使細(xì)胞因子或重組蛋???不會(huì)粘附于管壁。Recombinant Human BD-1, 47a.a.所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
產(chǎn)品描述
Recombinant Human BD-1, 47a.a.
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產(chǎn)品編號(hào)
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產(chǎn)品名稱
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產(chǎn)品包裝
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產(chǎn)品價(jià)格
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XY5799-1mg
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Recombinant
Human BD-1, 47a.a.
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1mg
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15444.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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1672
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P60022
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E. coli
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47aa
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5.1kDa
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－
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About this
Antibody
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Name
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Recombinant
Human BD-1, 47a.a. (Recombinant Human β-defensin 1, 47a.a.;
rHuBD-1, 47a.a.)；重組人β-防御素1，47a.a.
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Synonyms
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Beta-defensin
1; BD-1; hBD-1; Defensin, beta 1; DEFB1; BD1; HBD1
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Purity
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>98% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The biological activity
determined by a chemotaxis bioassay using CD34+ dendritic cells is in a concentration
range of 100.0-1000.0ng/ml.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4,
130mM NaCl.
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Endotoxin
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Less than 1EU/μg of rHuBD-1, 47a.a. as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should
be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Defensins
(alpha and beta) are cationic peptides with antimicrobial activity against
Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses. They
are 2-6kDa proteins and take important roles in innate immune system. On the
basis of their size and pattern of disulfide bonding, mammalian defensins are
classified into alpha, beta and theta categories. β-Defensins contain a six-cysteine motif that forms three
intra-molecular disulfide bonds. Four human β-defensins
have been identified and they are expressed on some leukocytes and at
epithelial surfaces. Because β-defensins is cationic
peptides, they can therefore interact with the membrane of invading microbes,
which are negative due to lipopolysaccharides (LPS) and lipoteichoic acid
(LTA) found in the cell membrane. Especially, they have higher affinity to
the binding site compared to Ca2+ and Mg2+ ions. Furthermore, they can affect the
stability of the membrane. The β-defensin proteins
are expressed as the C-terminal portion of precursors and are released by
proteolytic cleavage of a signal sequence and, in the case of BD-1 (36a.a.),
a propeptide region. Beta-defensin 1 may play a role in the pathogenesis of
severe sepsis. Variation in human Beta Defensin-1 contributes to asthma
diagnosis, with apparent gender-specific effects. Variation in human β-defensins 1 contributes to asthma diagnosis, with apparent
gender-specific effects. Human BD1 is down-regulated in human prostatic and
renal carcinomas.
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Amino Acid
Sequence
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GNFLTGLGHR SDHYNCVSSG GQCLYSACPI
FTKIQGTCYR GKAKCCK
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包裝清單:
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產(chǎn)品編號(hào)
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產(chǎn)品名稱
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包裝
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XY5799-5μg
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Recombinant
Human BD-1, 47a.a.
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5μg
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XY5799-25μg
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Recombinant
Human BD-1, 47a.a.
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25μg
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XY5799-100μg
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Recombinant
Human BD-1, 47a.a.
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100μg
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XY5799-1mg
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Recombinant
Human BD-1, 47a.a.
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1mg
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-
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說明書
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1份
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保存條件:
-20℃或更低溫度保存，至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活，所以**配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液)，須分裝后-20℃或更低溫度凍存，以避免反復(fù)凍融。
注意事項(xiàng):
由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
本產(chǎn)品**于專業(yè)人員的科學(xué)研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
為了您的**和健康，請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
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