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- 產(chǎn)品名稱：Recombinant Human IL-36γ, 169a.a.
- 產(chǎn)品型號(hào)：
- 產(chǎn)品展商：XYbscience
- 產(chǎn)品文檔：無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Recombinant Human IL-36γ, 169a.a.由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)???位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。Recombinant Human IL-36γ, 169a.a.所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
產(chǎn)品描述
Recombinant Human IL-36γ, 169a.a.
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產(chǎn)品編號(hào)
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產(chǎn)品名稱
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產(chǎn)品包裝
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產(chǎn)品價(jià)格
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XY264-1mg
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Recombinant
Human IL-36γ, 169a.a.
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1mg
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26773.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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56300
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Q9NZH8
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E. coli
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169aa
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18.7kDa
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－
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About this
protein
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Name
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Recombinant
Human IL-36γ, 169a.a. (Recombinant Human Interleukin-36γ, 169a.a.; rHuIL-36γ, 169a.a.)；重組人白細(xì)胞介素36γ，169a.a.
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Synonyms
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IL36G; IL1E;
IL1F9; IL1H1; IL1RP2; UNQ2456/PRO5737
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The specific activity is
determined by its binding ability in a functional ELISA. Immobilized rHuIL-36γ at 1μg/ml can bind recombinant human IL-1
Rrp2 Fc Chimera with a range of 0.15-5μg/ml.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHuIL-36γ, 169a.a. as determined by
LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should
be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interleukin-36
(IL-36) is a pro-inflammatory cytokine which plays an important role in the
pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and
IL-1F9) are IL-1 family members that signal through the IL-1 receptor family
members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. IL-36γ is
secreted when transfected into 293-T cells and it could constitute part of an
independent signaling system analogous to interleukin-1 alpha (IL-1A), beta
(IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1).
Furthermore, IL-36γ also can function as an agonist
of NF-kappa B activation through the orphan IL-1-receptor-related protein 2.
Recombinant human IL-36γ is synthesized as a 19kDa,
169 amino acid (a.a.) protein that contains no signal sequence, no prosegment
and no potential N-linked glycosylation site. Human to mouse, IL-36γ shares 53%a.a. identity. Within the family, IL-36γ shares about 25%~55%a.a. sequence identity with IL-1RA, IL-1β, IL-36RA, IL-36α, IL-37, IL-36β and IL-1F10.
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Amino Acid
Sequence
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MRGTPGDADG GGRAVYQSMC KPITGTINDL
NQQVWTLQGQ NLVAVPRSDS VTPVTVAVIT CKYPEALEQG RGDPIYLGIQ NPEMCLYCEK VGEQPTLQLK
EQKIMDLYGQ PEPVKPFLFY RAKTGRTSTL ESVAFPDWFI ASSKRDQPII LTSELGKSYN TAFELNIND
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包裝清單:
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產(chǎn)品編號(hào)
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產(chǎn)品名稱
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包裝
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XY264-2μg
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Recombinant
Human IL-36γ, 169a.a.
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2μg
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XY264-10μg
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Recombinant
Human IL-36γ, 169a.a.
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10μg
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XY264-100μg
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Recombinant
Human IL-36γ, 169a.a.
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100μg
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XY264-1mg
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Recombinant
Human IL-36γ, 169a.a.
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1mg
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-
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說(shuō)明書
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1份
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保存條件:
-20℃或更低溫度保存，至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活，所以**配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液)，須分裝后-20℃或更低溫度凍存，以避免反復(fù)凍融。
注意事項(xiàng):
由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
本產(chǎn)品**于專業(yè)人員的科學(xué)研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
為了您的**和健康，請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
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