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- 產(chǎn)品名稱(chēng)：Recombinant Human IL-36α, 153a.a.
- 產(chǎn)品型號(hào)：
- 產(chǎn)品展商：XYbscience
- 產(chǎn)品文檔：無(wú)相關(guān)文檔
簡(jiǎn)單介紹
Recombinant Human IL-36α, 153a.a.由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。Recombinant Human IL-36α, 153a.a.所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
產(chǎn)品描述
Recombinant Human IL-36α, 153a.a.
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產(chǎn)品編號(hào)
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產(chǎn)品名稱(chēng)
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產(chǎn)品包裝
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產(chǎn)品價(jià)格
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XY250-1mg
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Recombinant
Human IL-36α, 153a.a.
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1mg
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27053.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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27179
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Q9UHA7
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E. coli
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153aa
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17.1kDa
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－
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About this
protein
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Name
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Recombinant
Human IL-36α, 153a.a. (Recombinant Human Interleukin-36α, 153a.a.; rHuIL-36α, 153a.a.)；重組人白細(xì)胞介素36α，153a.a.
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Synonyms
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IL36A; FIL1E;
IL1E; IL1F6
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Purity
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>95% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by
inducing IL-8 secretion in human preadipocytes is less than 10ng/ml,
corresponding to a specific activity of >1.0×105IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 20mM Tris, 300mM
NaCl, pH8.0, 0.1% Tween 80.
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Endotoxin
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Less than 1EU/μg of rHuIL-36α, 153a.a. as determined by
LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Interleukin-36
(IL-36) is a pro-inflammatory cytokine which plays an important role in the
pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and
IL-1F9) are IL-1 family members that signal through the IL-1 receptor family
members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. Studies showed IL-36α is mainly found in skin and lymphoid tissues, but also in fetal
brain, trachea, stomach and intestine. Notably, IL-36 alpha is the only novel
IL-1 family member expressed on T cells. Recombinant human interleukin-36
alpha (153a.a.) contains 153 amino acids residues which is a single
non-glycosylated polypeptide and it shares 57-68%a.a. sequence identity with
mouse, rabbit, equine and bovine IL-36α and
27-57%a.a. sequence identity with other novel IL-1 family members.
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Amino Acid
Sequence
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KIDTPQQGSI QDINHRVWVL QDQTLIAVPR
KDRMSPVTIA LISCRHVETL EKDRGNPIYL GLNGLNLCLM CAKVGDQPTL QLKEKDIMDL YNQPEPVKSF
LFYHSQSGRN STFESVAFPG WFIAVSSEGG CPLILTQELG KANTTDFGLT MLF
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包裝清單:
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產(chǎn)品編號(hào)
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產(chǎn)品名稱(chēng)
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包裝
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XY250-2μg
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Recombinant
Human IL-36α, 153a.a.
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2μg
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XY250-10μg
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Recombinant
Human IL-36α, 153a.a.
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10μg
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XY250-100μg
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Recombinant
Human IL-36α, 153a.a.
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100μg
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XY250-1mg
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Recombinant
Human IL-36α, 153a.a.
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1mg
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-
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說(shuō)明書(shū)
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1份
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保存條件:
-20℃或更低溫度保存，至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活，所以**配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液)，須分裝后-20℃或更低溫度凍存，以避免反復(fù)凍融。
注意事項(xiàng):
由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
本產(chǎn)品**于專(zhuān)業(yè)人員的科學(xué)研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
為了您的**和健康，請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
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