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- 產(chǎn)品名稱：Recombinant Human IL-36α, 158a.a.
- 產(chǎn)品型號(hào)：
- 產(chǎn)品展商：XYbscience
- 產(chǎn)品文檔：無相關(guān)文檔
簡(jiǎn)單介紹
Recombinant Human IL-36α, 158a.a.由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)??位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。Recombinant Human IL-36α, 158a.a.所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
產(chǎn)品描述
Recombinant Human IL-36α, 158a.a.
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產(chǎn)品編號(hào)
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產(chǎn)品名稱
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產(chǎn)品包裝
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產(chǎn)品價(jià)格
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XY237-1mg
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Recombinant
Human IL-33
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1mg
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26773.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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90865
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O95760
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E. coli
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159aa
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17.9kDa
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－
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About this
protein
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Name
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Recombinant
Human IL-33 (Recombinant Human Interleukin-33; rHuIL-33)；重組人白細(xì)胞介素33
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Synonyms
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C9orf26;
DVS27; NF-HEV; C9orf26chromosome 9 open reading frame 26 (NF-HEV); DKFZXY86H0523;
DVS27; DVS27-related protein; IL1F11; IL-1F11; IL-33; interleukin 33; Interleukin-1
family member 11; interleukin-33; NFHEV; NF-HEVNFEHEV; Nuclear factor from
high endothelial venules; RP11-575C20.2
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using murine D10S cells is less than 0.05ng/ml,
corresponding to a specific activity of >2.0×107IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in 20mM PB, 150mM
NaCl, 1mM EDTA, pH7.4.
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Endotoxin
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Less than 1EU/μg of rHuIL-33 as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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IL-33, encoded
by IL-33 gene located on the Chr.9 in humans, is a 30kDa proinflammatory
protein belonging to the IL-1 superfamily and it shares less than 20%a.a.
sequence identity with other members. IL-33 secreted by high endothelial
venules at high levels, which is found in tonsils, peyer patches and
mesenteric lymph nodes, but not in placenta. It is upregulated in arterial
smooth muscle, dermal fibroblasts, and keratinocytes following IL1α or IL1β stimulation. It elicits its
biological effects by interacting with IL1RL1/ST2 and its stimulation
recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of
MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL-33 mature protein has
52-58%a.a. sequence identity with mouse and rat IL-33.
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Amino Acid
Sequence
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SITGISPITE YLASLSTYND QSITFALEDE
SYEIYVEDLK KDEKKDKVLL SYYESQHPSN ESGDGVDGKM LMVTLSPTKD FWLHANNKEH SVELHKCEKP
LPDQAFFVLH NMHSNCVSFE CKTDPGVFIG VKDNHLALIK VDSSENLCTE NILFKLSET
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包裝清單:
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產(chǎn)品編號(hào)
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產(chǎn)品名稱
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包裝
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XY237-2μg
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Recombinant
Human IL-33
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2μg
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XY237-10μg
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Recombinant
Human IL-33
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10μg
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XY237-100μg
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Recombinant
Human IL-33
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100μg
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XY237-1mg
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Recombinant
Human IL-33
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1mg
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-
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說明書
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1份
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保存條件:
-20℃或更低溫度保存，至少一年有效。由于蛋白的每次凍融均會(huì)引起部分失活，所以**配制成相應(yīng)濃度的儲(chǔ)存液后(請(qǐng)根據(jù)產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液)，須分裝后-20℃或更低溫度凍存，以避免反復(fù)凍融。
注意事項(xiàng):
由于有些塑料管壁對(duì)某些蛋白有較強(qiáng)的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預(yù)先封閉塑料管壁上的蛋白結(jié)合位點(diǎn)，使細(xì)胞因子或重組蛋白不會(huì)粘附于管壁。所以一定要使用產(chǎn)品簡(jiǎn)介中Reconstitution一欄的信息配制儲(chǔ)存液。
本產(chǎn)品**于專業(yè)人員的科學(xué)研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
為了您的**和健康，請(qǐng)穿實(shí)驗(yàn)服并戴一次性手套操作。
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