- 如果您對該產(chǎn)品感興趣的話，可以
- 產(chǎn)品名稱：Recombinant Human IL-13, Variant
- 產(chǎn)品型號：
- 產(chǎn)品展商：XYbscience
- 產(chǎn)品文檔：無相關(guān)文檔
簡單介紹
Recombinant Human IL-13, Variant由于有些塑料管壁對某些蛋白有較強的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預先封閉塑料管壁上的蛋白結(jié)合位點，使細胞因子或重組蛋白不會粘附于管壁。Recombinant Human IL-13, Variant所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液。
產(chǎn)品描述
Recombinant Human IL-13, Variant
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產(chǎn)品編號
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產(chǎn)品名稱
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產(chǎn)品包裝
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產(chǎn)品價格
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XY183-1mg
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Recombinant
Human IL-13, Variant
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1mg
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26773.00元
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Species
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Gene ID
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Accession
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Source
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Length
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MW
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Tag
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Human
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3596
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P35225
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E. coli
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112aa
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12.3kDa
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－
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About this
protein
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Name
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Recombinant
Human IL-13, Variant (Recombinant Human Interleukin-13, Variant; rHuIL-13,
Variant)；重組人白細胞介素13變體
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Synonyms
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IL-13; P600
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Purity
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>97% by
SDS-PAGE and HPLC analyses.
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Biological
Activity
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Fully
biologically active when compared to standard. The ED50 as determined by a
cell proliferation assay using human TF-1 cells is less than 0.5ng/ml,
corresponding to a specific activity of >2.0×106IU/mg.
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Physical
Appearance
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Sterile
Filtered White lyophilized (freeze-dried) powder.
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Formulation
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Lyophilized
from a 0.2μm filtered concentrated solution in PBS, pH7.2, with
5% trehalose.
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Endotoxin
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Less than 1EU/μg of rHuIL-13, Variant as determined by LAL method.
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Reconstitution
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We recommend
that this vial be briefly centrifuged prior to opening to bring the contents
to the bottom. Reconstitute in sterile distilled water or aqueous buffer
containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions
should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in
appropriate buffered solutions.
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Category
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Cytokine
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Background
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Human
Interleukin-13 (IL-13) is expressed by the IL13 gene located on the
chromosome 5. IL-13 is a 132 amino acid protein containing a proposed 20
amino acid signal peptide, and shares approximately 30% amino acid sequence
homology to human IL-4. Additionally, the two cytokines exhibit overlapping
biological activities. Human IL-13 is produced by activated Th0, Th1-like
Th2-like and CD8 T cells. Similarly to IL-4, IL-13 has multiple effects on
the differentiation and functions of monocytes/macrophages. IL-13 can
suppress the cytotoxic functions of monocytes/macrophages.
IL-13 variant is a natural variant of IL-13 and has a Q instead of R112 of
wild type, which associated with increased risk for asthma development and at
homozygosity associated with higher levels of serum total IgE in some
allergic rhinitis patients.
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Amino Acid
Sequence
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GPVPPSTALR ELIEELVNIT QNQKAPLCNG
SMVWSINLTA GMYCAALESL INVSGCSAIE KTQRMLSGFC PHKVSAGQFS SLHVRDTKIE VAQFVKDLLL
HLKKLFREGQ FN
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包裝清單:
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產(chǎn)品編號
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產(chǎn)品名稱
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包裝
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XY183-2μg
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Recombinant
Human IL-13, Variant
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2μg
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XY183-10μg
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Recombinant
Human IL-13, Variant
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10μg
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XY183-100μg
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Recombinant
Human IL-13, Variant
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100μg
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XY183-1mg
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Recombinant
Human IL-13, Variant
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1mg
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說明書
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1份
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保存條件:
-20℃或更低溫度保存，至少一年有效。由于蛋白的每次凍融均會引起部分失活，所以**配制成相應濃度的儲存液后(請根據(jù)產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液)，須分裝后-20℃或更低溫度凍存，以避免反復凍融。
注意事項:
由于有些塑料管壁對某些蛋白有較強的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很難與管壁分離。而載體蛋白(Carrier protein，如0.1% BSA等)的主要作用是預先封閉塑料管壁上的蛋白結(jié)合位點，使細胞因子或重組蛋白不會粘附于管壁。所以一定要使用產(chǎn)品簡介中Reconstitution一欄的信息配制儲存液。
本產(chǎn)品**于專業(yè)人員的科學研究用，不得用于臨床診斷或**，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
為了您的**和健康，請穿實驗服并戴一次性手套操作。
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