中胚層誘導(dǎo)早期反應(yīng)蛋白2抗體
規(guī)格：1mg/1ml
英文名： MIER2
別名： KIAA1193. mesoderm induction early response 1, family member 2; Mesoderm induction early response protein 2; Mi-er2; Mier2; MIER2_HUMAN.
分子量： 60kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：manKLH conjugated synthetic peptide derived from human MIER2
交叉反應(yīng)：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
細(xì)胞定位：細(xì)胞核
中胚層誘導(dǎo)早期反應(yīng)蛋白2抗體產(chǎn)品介紹：background: MIER2 is a 545 amino acid protein encoded by a gene that maps to human chromosome 19p13.3. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. 中胚層誘導(dǎo)早期反應(yīng)蛋白2抗體Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. Function: Transcriptional repressor (By similarity). Subcellular 中胚層誘導(dǎo)早期反應(yīng)蛋白2抗體Location: Nucleus (By similarity). Similarity: Contains 1 ELM2 domain. Contains 1 SANT domain. Gene ID: 54531 Database links: Entrez Gene: 54531 Human SwissProt: Q8N344 Human Unigene: 101891 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
中胚層誘導(dǎo)早期反應(yīng)蛋白2抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
儲(chǔ)存條件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Rabbit
外觀： Lyophilized or Liquid
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