凋亡加強結(jié)構(gòu)域蛋白8抗體
規(guī)格：1mg/1ml
英文名： CARD8
別名： Apoptotic protein NDPP 1; Apoptotic protein NDPP1; CARD 8; CARD inhibitor of NF kappa B activating ligand; CARD inhibitor of NF kappaB activating ligand; CARD inhibitor of NF kappaB activating ligands
分子量： 49kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CARD8
交叉反應(yīng)：Human,
細胞定位：細胞核 細胞漿
凋亡加強結(jié)構(gòu)域蛋白8抗體產(chǎn)品介紹：background: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases. Function: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function 凋亡加強結(jié)構(gòu)域蛋白8抗體would be the activation of proinflammatory caspases. [SUBUNIT] May form homodimers. Interacts with NEMO and DRAL. Binds to caspase-1, CARD16/pseudo-ICE and CARD18/ICEBERG. Interacts with FNBP3 (By similarity). Interacts with NALP2 NACHT domain. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: High expression in lung, ovary, testis and placenta. Lower expression in heart, kidney and liver. Also expressed in spleen, lymph node and bone marrow. Similarity: Contains 1 CARD domain. Gene ID: 22900 Database links:凋亡加強結(jié)構(gòu)域蛋白8抗體 Entrez Gene: 22900 Human Omim: 609051 Human SwissProt: Q9Y2G2 Human Unigene: 446146 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
凋亡加強結(jié)構(gòu)域蛋白8抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細胞生物 細胞凋亡
儲存條件：
來源： Rabbit
外觀： Lyophilized or Liquid
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