BCL10結(jié)合蛋白和激活核轉(zhuǎn)錄因子抗體
規(guī)格：1mg/1ml
英文名： CARD10
別名： Bcl10 binding protein and activator of NFKB; BIMP1; CAR10_HUMAN; CARD 10; CARD-containing MAGUK 3; CARD-containing MAGUK protein 3; CARD10; Carma 3; CARMA3; Caspase Recruitment Domain family member 10
分子量： 116kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CARD10
交叉反應(yīng)：Human, Mouse, Rat, Dog, Monkey,
細(xì)胞定位：
BCL10結(jié)合蛋白和激活核轉(zhuǎn)錄因子抗體產(chǎn)品介紹：background: Membrane-associated guanylate kinase (MAGUK) family members function as molecular scaffolds for the assembly of multiprotein complexes localizing to the plasma membrane. Several mammalian proteins related to the Drosophila tumor suppressor discs-large (dlg) gene product belong to the MAGUK family, including the caspase recruitment domain (CARD) protein family with the exception of CARD9. The CARD domain consists of 6 or 7 antiparallel alpha helices. CARD family members participate in apoptosis signaling through highly specific protein-protein homophilic interactions. CARD 10 (also designated CARD-containing BCL10結(jié)合蛋白和激活核轉(zhuǎn)錄因子抗體MAGUK protein 3 or Carma 3) interacts with BCL-10 to activate NFⅹB. CARD10 is expressed in a variety of ***** and fetal tissues, including heart, kidney and liver, and in multiple cancer cell lines. Function: Activates NF-kappa-B via BCL10 and IKK. Tissue Specificity: Detected in ***** heart, kidney and liver; lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidneyBCL10結(jié)合蛋白和激活核轉(zhuǎn)錄因子抗體. Similarity: Contains 1 CARD domain. Gene ID: 607209 Database links: Entrez Gene: 29775 Human Entrez Gene: 105844 Mouse Omim: 607209 Human SwissProt: Q9BWT7 Human SwissProt: P58660 Mouse Unigene: 57973 Human Unigene: 17629 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)BCL10結(jié)合蛋白和激活核轉(zhuǎn)錄因子抗體品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 **學(xué) 細(xì)胞凋亡
儲(chǔ)存條件：
來(lái)源： Rabbit
外觀： Lyophilized or Liquid
- 溫馨提示：為規(guī)避購(gòu)買風(fēng)險(xiǎn)，建議您在購(gòu)買前務(wù)必確認(rèn)供應(yīng)商資質(zhì)與產(chǎn)品質(zhì)量。
- 免責(zé)申明：以上內(nèi)容為注冊(cè)會(huì)員自行發(fā)布，若信息的真實(shí)性、合法性存在爭(zhēng)議，平臺(tái)將會(huì)監(jiān)督協(xié)助處理，歡迎舉報(bào)