細(xì)胞毒顆粒相關(guān)蛋白TIA-1抗體
規(guī)格：1mg/1ml
英文名： TIA1
別名： Cytotoxic granule associated RNA binding protein 1; Cytotoxic granule associated RNA binding protein; mTIA-1; Nucleolysin TIA 1 isoform p40; Nucleolysin TIA-1 isoform p40; Nucleolysin TIA1 isoform p40
分子量： 43kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類(lèi)型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TIA1
交叉反應(yīng)：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
細(xì)胞定位：細(xì)胞核 細(xì)胞漿
細(xì)胞毒顆粒相關(guān)蛋白TIA-1抗體產(chǎn)品介紹：background: Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. Function: Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic細(xì)胞毒顆粒相關(guān)蛋白TIA-1抗體 lymphocyte target cells. May be involved in apoptosis. Subcellular Location: Cytoplasmic granule. Nucleus. Note=Accumulates in cytoplasmic stress granules (SG) following cellular damage. Similarity: Contains 3 RRM (RNA recognition motif) domains. Gene ID: 7072 Database links: Entrez Gene: 7072 Human Entrez Gene: 21841 Mouse Entrez Gene: 312510 Rat Omim: 603518 Human SwissProt: P31483 細(xì)胞毒顆粒相關(guān)蛋白TIA-1抗體Human SwissProt: P52912 Mouse Unigene: 413123 Human Unigene: 333219 Mouse Unigene: 198158 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)細(xì)胞毒顆粒相關(guān)蛋白TIA-1抗體品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 **學(xué) 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 表觀(guān)遺傳學(xué)
儲(chǔ)存條件：
來(lái)源： Rabbit
外觀(guān)： Lyophilized or Liquid
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