卷曲螺旋結(jié)構(gòu)域蛋白139抗體
規(guī)格：1mg/1ml
英文名： CCDC139
別名： CCDC139; Coiled coil domain containing protein 139; DOBI; FLJ32312; MGC126729; Putative tRNA pseudouridine synthase Pus10; tRNA pseudouridine 55 synthase; tRNA uridine isomerase; PUS10_HUMAN.
分子量： 60kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PUS10/CC
交叉反應：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
細胞定位：
卷曲螺旋結(jié)構(gòu)域蛋白139抗體產(chǎn)品介紹：background: Pseudouridination is the isomerization of uridine to pseudouridine. It is the most common posttranscriptional nucleotide modification found in RNA. It is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones which facilitate the correct folding and assembly of tRNAs. Function: Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the卷曲螺旋結(jié)構(gòu)域蛋白139抗體 universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death. Post-translational modifications: Proteolytically cleaved during TRAIL-induced cell death. Cleaved, in vitro, either by caspase-3 or caspase-8. Similarity: Belongs to the卷曲螺旋結(jié)構(gòu)域蛋白139抗體 pseudouridine synthase Pus10 family. Database links: UniProtKB/Swiss-Prot: Q3MIT2.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卷曲螺旋結(jié)構(gòu)域蛋白139抗體產(chǎn)品應用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細胞生物 信號轉(zhuǎn)導 細胞凋亡 表觀遺傳學
儲存條件：
來源： Rabbit
外觀： Lyophilized or Liquid
- 溫馨提示：為規(guī)避購買風險，建議您在購買前務必確認供應商資質(zhì)與產(chǎn)品質(zhì)量。
- 免責申明：以上內(nèi)容為注冊會員自行發(fā)布，若信息的真實性、合法性存在爭議，平臺將會監(jiān)督協(xié)助處理，歡迎舉報