鋅指蛋白127抗體
規(guī)格：1mg/1ml
英文名： ZNF127
別名： D15S9; Makorin ring finger protein 3; Mkrn3; MKRN3_HUMAN; Probable E3 ubiquitin-protein ligase makorin-3; RING finger protein 63; RNF63; ZFP127; Zinc finger protein 127; ZNF127.
分子量： 57kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類(lèi)型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF127
交叉反應(yīng)：Human, Mouse, Rat, Pig, Rabbit,
細(xì)胞定位：細(xì)胞核
鋅指蛋白127抗體產(chǎn)品介紹：background: The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008] Function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Tissue Specificity: Expressed in testis, brain, heart and kidney. Ubiquitously detected at low levels throughout the entire embryo, but expression is highest in the ventricular layers of the brain. DISEASE: Expressed at the blastocyst stage and the embryonic days 8-17, as well as in undifferentiated and differentiated embryonic stem cells. Expressed in the arcuate nucleus of both male and female animals. Levels of expression are highest on postnatal days 10鋅指蛋白127抗體 and 12, begin to decline on day 15, and reaches a nadir by days 18 to 22, at which time expression is 10 to 20% of the levels detected at 10 days. The timing of the decline in protein expression correlated with the ages at which arcuate KISS1 and TAC2 have been shown to increase, heralding the onset of puberty. Similarity: Contains 3 C3H1-type zinc fingers. Contains 1 RING-type zinc finger. Database links: Entrez 鋅指蛋白127抗體Gene: 7681 Human Entrez Gene: 22652 Mouse Entrez Gene: 292988 Rat Omim: 603856 Human SwissProt: Q13064 Human SwissProt: Q60764 Mouse Unigene: 679587 Human Unigene: 72964 Human Unigene: 146 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)鋅指蛋白127抗體品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué)
儲(chǔ)存條件：
來(lái)源： Rabbit
外觀： Lyophilized or Liquid
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