蓖麻**B鏈抗體
規(guī)格：1mg/1ml
英文名： Ricin B chain
別名： Ricin toxin B chain; RCA 60; Ricin B lectin; Ricin chain B; Ricin precursor; rRNA N-glycosidase; RT B; RTB.
分子量： 29kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Ricin B
交叉反應(yīng)：Reacts with Ricinus communis (Castor Bean plant).
細胞定位：
蓖麻**B鏈抗體產(chǎn)品介紹：Function: Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the蓖麻**B鏈抗體 entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity). Subunit: Disulfide-linked dimer of A and B chains.The B chain is composed of two domains, each domain consists of 3 homologous subdomains (alpha, beta, gamma).蓖麻**B鏈抗體 Gene ID: 8287993 Database links: Entrez Gene: 8287993 Ricinus communis Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蓖麻**B鏈抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
儲存條件：
來源： Rabbit
外觀： Lyophilized or Liquid
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