鋅指蛋白186抗體
規(guī)格：1mg/1ml
英文名： ZNF186
別名： Cos 12; hZNF2; ZNF73; Zinc finger protein 186; Zinc finger protein 73; ZNF 186; ZNF 73; ZNF186.
分子量： 38kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF186
交叉反應(yīng)：Human, Mouse,
細(xì)胞定位：細(xì)胞核
鋅指蛋白186抗體產(chǎn)品介紹：background: ZNF73 may be involved in transcriptional regulation. Function: E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. Subunit: Homodimer. Interacts with UBE2A and UBE2B, one homodimer binding one molecule of UBE2B. Interacts with HLTF and SHPRH. Interacts with SPRTN; leading to enhance chromatin association 鋅指蛋白186抗體of RAD18 and RAD18-mediated PCNA ubiquitination and translesion DNA synthesis. Subcellular Location: Nuclear. Similarity: Belongs to the RAD18 family. Contains 1 RING-type zinc finger. Contains 1 SAP domain. Contains 1 UBZ-type zinc finger. Database鋅指蛋白186抗體 links: Entrez Gene: 7624 Human Omim: 194547 Human SwissProt: O43830 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品應(yīng)用：鋅指蛋白186抗體WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué)
儲存條件：
來源： Rabbit
外觀： Lyophilized or Liquid