線粒體鐵轉運蛋白2抗體
規(guī)格:1mg/1ml
英文名: Mitoferrin 2/SLC25A28
別名: MFRN2; Mitochondrial iron transporter 2; Mitochondrial RNA splicing protein 3/4; Mitoferrin 2; Mitoferrin2; Mitoferrin-2; MRS3/4; MRS4L; NPD016; Putative mitochondrial solute carrier; MFRN2_HUMAN; SLC
分子量: 39kDa
儲存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型:Polyclonal
亞型:IgG
純化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Mitoferr
交叉反應:Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
線粒體鐵轉運蛋白2抗體細胞定位:細胞漿 線粒體
產(chǎn)品介紹:background: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin線粒體鐵轉運蛋白2抗體 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2. Function: SLC25A28 is a mitochondrial iron transporter that mediates iron uptake. It is probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. Subcellular Location: Mitochondrion inner membrane; Multi pass membrane protein. Note: Isoform 1 and isoform 2 are both localized in the mitochondrion. Tissue Specificity: Ubiquitous. Expressed in placenta, lung, kidney, pancreas, liver, brain, skeletal muscle and heart線粒體鐵轉運蛋白2抗體. Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family. Contains 3 Solcar repeats. Gene ID: 81894 Database links: Entrez Gene: 538529 Cow Entrez Gene: 486837 Dog Entrez Gene: 81894 Human Entrez Gene: 246696 Mouse Entrez Gene: 688811 Rat Omim: 609767 Human SwissProt: Q96A46 Human SwissProt: Q8R0Z5 Mouse SwissProt: B2RYH0 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
線粒體鐵轉運蛋白2抗體產(chǎn)品應用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領域:腫瘤 細胞生物 神經(jīng)生物學 信號轉導 新陳代謝 線粒體
儲存條件:
來源: Rabbit
外觀: Lyophilized or Liquid
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