Caspase激活的脫氧核糖核酸酶抑制劑抗體
規(guī)格：1mg/1ml
英文名： ICAD
別名： DFF-45 Beta; ICAD; ICAD L; ICAD S; Caspase activated deoxyribonuclease inhibitor short form; DFF 1; DFF 45; DFF-45; DFF alpha; DFF1; DFF35; DFF45; DFFA; Dffa DNA fragmentation factor, alpha subunit; D
分子量： 36kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ICAD
交叉反應(yīng)：Human, Mouse, Rat,
Caspase激活的脫氧核糖核酸酶抑制劑抗體細(xì)胞定位：
產(chǎn)品介紹：background: Caspase-activated deoxyribonuclease(CAD) also designated DNA fragmentation factor 45 kDa subunit (DFF-45)and Caspase-activated DNase. CAD is a nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. ICAD (DNA fragmentation factor alpha subunit) (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) is inhibitor of the caspase-activated DNase (DFF44). Function: Inhibitor of the caspase-activated DNase (DFF40). Caspase激活的脫氧核糖核酸酶抑制劑抗體Subunit: Heterodimer of DFFA and DFFB. Subcellular Location: Cytoplasm. Post-translational modifications: Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. Similarity: Contains 1 CIDE-N domain. Gene IDCaspase激活的脫氧核糖核酸酶抑制劑抗體: 1676 Database links: Entrez Gene: 1676 Human Omim: 601882 Human SwissProt: O00273 Human Unigene: 484782 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ICAD 是在細(xì)胞凋亡期誘導(dǎo)DNA分裂和染色體固縮的一種核酶，降解裸露的DNA 并誘導(dǎo)形態(tài)學(xué)變化。
Caspase激活的脫氧核糖核酸酶抑制劑抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 **學(xué) 染色質(zhì)和核信號 細(xì)胞凋亡 新陳代謝 表觀遺傳學(xué)
儲存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
外觀： Lyophilized or Liquid
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