降鈣素受體抗體
規(guī)格：1mg/1ml
英文名： Calcitonin receptor
別名： Calcitonin receptor precursor; Calcr; CRT; CT R; CTR; CTR1; CALCR_MOUSE; CT-R; CALCR_HUMAN.
分子量： 53kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse Calciton
交叉反應(yīng)：Mouse, Rat,
降鈣素受體抗體細(xì)胞定位：細(xì)胞膜
產(chǎn)品介紹：background: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] Function: This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric降鈣素受體抗體 guanosine triphosphate-binding protein that is sensitive to cholera toxin. Subunit: Interacts with GPRASP2. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2 family. Gene ID: 12311 Database links: Entrez Gene: 799 Human Entrez Gene: 12311 Mouse Entrez Gene: 116506 Rat Omim: 114131 Human SwissProt: P30988 Human SwissProt:降鈣素受體抗體 Q60755 Mouse SwissProt: P32214 Rat Unigene: 489127 Human Unigene: 4642 Mouse Unigene: 10062 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 降鈣素受體（Calcitonin receptor,CT-R)是G蛋白偶聯(lián)受體，有兩種受體亞型，CT-R可與多種配體結(jié)合，如CGRP、Amylin、Am等。CT-R在破骨細(xì)胞中含量*高，也存在于腎等多種器官組織內(nèi)。
降鈣素受體抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：腫瘤 **學(xué) 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞膜受體 G蛋白偶聯(lián)受體
儲存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
外觀： Lyophilized or Liquid
- 溫馨提示：為規(guī)避購買風(fēng)險，建議您在購買前務(wù)必確認(rèn)供應(yīng)商資質(zhì)與產(chǎn)品質(zhì)量。
- 免責(zé)申明：以上內(nèi)容為注冊會員自行發(fā)布，若信息的真實(shí)性、合法性存在爭議，平臺將會監(jiān)督協(xié)助處理，歡迎舉報