突觸素抗體/突觸相關(guān)蛋白-1
規(guī)格：1mg/1ml
英文名： SYAP1
別名： Synapse associated protein-1; synapse-associated protein 1-like; 2010110O17Rik, AW011796, DKFZp686K221, FLJ14495, FLJ44185, MGC94115, PRO3113, SYAP1; SYAP1_HUMAN; SAP-1.
分子量： 40kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SAP-1
交叉反應(yīng)：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
突觸素抗體/突觸相關(guān)蛋白-1細(xì)胞定位：細(xì)胞漿 細(xì)胞膜
產(chǎn)品介紹：background: SYAP1 (synapse-associated protein 1) is a 352 amino acid protein that is ubiquitously expressed in ***** tissues. SYAP1 contains one BSD domain which is a novel domain that is present in basal transcription factors, synapse-associated proteins and several hypothetical proteins. The BSD domain is characterized by three predicted alpha helices and by conserved tryptophan and phenylalanine residues,突觸素抗體/突觸相關(guān)蛋白-1 located at the C-terminus of the domain. The gene that encodes SYAP1 in humans is located on chromosome X. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. Similarity: Contains 1 BSD domain. Gene ID: 94056 Database links: Entrez Gene: 509355 Cow Entrez Gene: 94056 Human Entrez Gene: 67043 Mouse Entrez Gene: 302678 Rat SwissProt: Q96A49 Human SwissProt: Q9D5V6 Mouse Unigene: 729197 Human Unigene: 44207 Mouse Important Note: This product as supplied is突觸素抗體/突觸相關(guān)蛋白-1 intended for research use only, not for use in human, therapeutic or diagnostic applications. 突觸素SAP-1/SYP(Synaptophysin, FRG-4)是分布于突觸囊泡膜上含量豐富的糖蛋白之一，與遞質(zhì)釋放關(guān)系密切，并可影響突觸可塑性。突觸相關(guān)蛋白-1可作為神經(jīng)元和神經(jīng)***細(xì)胞的可靠標(biāo)記物用于神經(jīng)系統(tǒng)形態(tài)、功能和發(fā)育以及相關(guān)**的研究。對(duì)于SAP-1的功能及其具體作用機(jī)制，尚待進(jìn)一步研究。
突觸素抗體/突觸相關(guān)蛋白-1產(chǎn)品應(yīng)用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-200 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：細(xì)胞生物 **學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo)
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Rabbit
外觀： Lyophilized or Liquid
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