轉移生長因子β3抗體
規(guī)格：1mg/1ml
英文名： TGF beta 3 propeptide
別名： TGF beta 3; ARVD; FLJ16571; MGC105479; MGC118722; TGF beta 3; TGF beta3; TGF-beta-3; TGF-beta 3; TGFB 3; TGFB3; TGFB3_HUMAN; transforming growth factor beta 3; Transforming growth factor beta-3.
分子量： 30/47kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TGF-beta
交叉反應：Human, Mouse, Rat, Dog, Rabbit,
轉移生長因子β3抗體細胞定位：分泌型蛋白
產品介紹：background: The TGFBeta superfamily is composed of numerous growth and differentiation factors, including transforming growth factors Beta(TGFBeta) 1,2 and 3; placental transforming growth factor (PTGFBeta);growth /differentiation factors (GDFs); mullerian inhibiting substance (MIS);bone morphogenic proteins (BMPs);glial cell line-derived neurotrophic factor (GDNF);inhibins or activins (Alpha,Beta-A, Beta-B and Beta-C),Lefty and Nodal. Members of the TGF superfamily are involved in embryonic development and ***** tissue homeostasis. Function: Involved in embryogenesis and cell differentiation. Subunit: Homodimer; disulfide-linked. Interacts with ASPN. Subcellular Location: Secreted. DISEASE: Defects 轉移生長因子β3抗體in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. Similarity:轉移生長因子β3抗體 Belongs to the TGF-beta family. Gene ID: 7043 Database links: Entrez Gene: 7043 Human Entrez Gene: 21809 Mouse Entrez Gene: 25717 Rat Omim: 190230 Human SwissProt: P10600 Human SwissProt: P17125 Mouse SwissProt: Q07258 Rat Unigene: 592317 Human Unigene: 3992 Mouse Unigene: 7018 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 生長因子和**（ Growth Factor and Hormones） TGF是一種多效生長因子,對上皮細胞增值有潛在抑制作用,可抑制腫瘤生長，用于許多惡性腫瘤如:胃癌、肺癌、膀胱癌、腎癌、前列腺癌、結腸癌等多種惡性腫瘤的研究。分子量：47kDa。此抗體是TGFβ3 特異性抗體，與TGF-β1和TGF-β2沒有交叉反應。
轉移生長因子β3抗體產品應用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領域：信號轉導 干細胞 生長因子和**
儲存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
外觀： Lyophilized or Liquid
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