胃泌素抑制肽抗體
規(guī)格:1mg/1ml
英文名: GIP
別名: Gastric Inhibitory polypeptide; Gastric inhibitory polypeptide precursor; GIP; Glucose dependent insulinotropic polypeptide; Gastric Inhibitory Peptide; GIP_HUMAN; Glucose-dependent insulinotropic pol
分子量: 16kDa
儲存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型:Polyclonal
亞型:IgG
純化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GIP
交叉反應(yīng):Human, Mouse, Rat, Pig, Cow,
胃泌素抑制肽抗體細(xì)胞定位:分泌型蛋白
產(chǎn)品介紹:background: GIP (Gastric Inhibitory polypeptide ) belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. Mature GIP is a highly conserved 42 amino acid polypeptide belonging to the glucagon family.胃泌素抑制肽抗體 GIP is highly expressed as a pre-pro-protein in the duodenum and the jejunum. The mature secreted polypeptide acts as a potent stimulator of insulin secretion and a poor inhibitor of gastric acid secretion. Function: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. Subcellular Location: Secreted. Similarity: Belongs to the glucagon family. Gene ID: 2695 Database links: Entrez Gene: 2695 Human Omim: 137240 Human SwissProt: P09681 Human Unigene: 1454 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胃泌素抑制肽(GIP)是胃腸道的一種由42個(gè)氨基酸組成的多肽**,胃泌素抑制肽抗體又稱為葡萄糖依賴性促胰島素多肽(glucose-dependent insulinotropic peptide,GIP)他強(qiáng)烈抑制胃分泌和運(yùn)動,也可調(diào)節(jié)胰島素的釋放。GIP屬于Glucagon家族成員。
胃泌素抑制肽抗體產(chǎn)品應(yīng)用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域:信號轉(zhuǎn)導(dǎo) 生長因子和** 轉(zhuǎn)錄調(diào)節(jié)因子 糖尿病
儲存條件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源: Rabbit
外觀: Lyophilized or Liquid
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