鈣調(diào)節(jié)蛋白-1抗體
規(guī)格：1mg/1ml
英文名： Calponin 1
別名： Basic calponin; Calponin 1; Calponin-1; Calponin 1 basic smooth muscle; Calponin H1 smooth muscle; Calponin1; Calponins basic; CNN 1; CNN1; Sm Calp; SMCC; CNN1_HUMAN; Calponin H1; Calponin1; Sm Calp;
分子量： 33kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Calponin
交叉反應(yīng)：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
鈣調(diào)節(jié)蛋白-1抗體細(xì)胞定位：
產(chǎn)品介紹：background: Calponin, a calmodulin, is a thin filament associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. Function: Thin filament-associated protein that is implicated in the regulation and modulation of smooth 鈣調(diào)節(jié)蛋白-1抗體muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). Subunit: Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1. Tissue Specificity: Smooth muscle, and tissues containing significant amounts of smooth muscle. Similarity: Belongs to the calponin family. Contains 3 calponin-like repeats. Contains 1 CH (calponin-homology) domain. Gene ID: 1264 Database links: Entrez Gene: 1264 Human Entrez Gene: 484937 Dog Entrez Gene: 12797 Mouse Entrez Gene: 396911 Pig Entrez Gene: 65204 Rat Omim: 鈣調(diào)節(jié)蛋白-1抗體600806 Human SwissProt: P51911 Human SwissProt: Q08091 Mouse SwissProt: Q08092 Pig SwissProt: Q08290 Rat Unigene: 465929 Human Unigene: 4356 Mouse Unigene: 31788 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Calponin1是一種激動(dòng)蛋白結(jié)合蛋白，是平滑肌特有的一種蛋白，可以與肌動(dòng)蛋白、原肌球蛋白和鈣調(diào)素結(jié)合,具有抑制平滑肌細(xì)胞收縮的功能，主要用于平滑肌腫瘤和乳腺等組織中的肌上皮細(xì)胞分布的研究。
鈣調(diào)節(jié)蛋白-1抗體產(chǎn)品應(yīng)用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：心血管 信號(hào)轉(zhuǎn)導(dǎo) 干細(xì)胞 細(xì)胞骨架
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Rabbit
外觀： Lyophilized or Liquid
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