分泌素受體抗體
規(guī)格：1mg/1ml
英文名： Secretin receptor
別名： 6530402O03Rik, MGC102218, MGC93381, SCTR, SR; Secretin receptor; SCT-R; SCTR_HUMAN.
分子量： 46kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類(lèi)型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from the middle of
交叉反應(yīng)：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
分泌素受體抗體細(xì)胞定位：細(xì)胞膜
產(chǎn)品介紹：background: The receptor for secretin is a class 2 (or class B) G protein coupled receptor that signals through Gs to stimulate cAMP production. Along with its traditional role in the pancreas, studies in secretin-deficient mice have shown miscommunication between the CA3 Schaffer collateral and CA1 pyramidal neurons, causing a deficiency in synaptic transmission. This miscommunication of CA1 dendrites is found in Autism, Rett Syndrome, and most forms of mental retardation, suggesting secretin could be a potential target for treatment of these disorders.分泌素受體抗體 Function: This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2 family. Gene ID: 6344 Database links: Entrez Gene: 6344 Human Omim: 182098 Human SwissProt: P47872 Human Unigene: 42091 Human Important Note: 分泌素受體抗體This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
分泌素受體抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：信號(hào)轉(zhuǎn)導(dǎo) 生長(zhǎng)因子和** 細(xì)胞膜受體 ***病 細(xì)胞類(lèi)型標(biāo)志物
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Rabbit
外觀： Lyophilized or Liquid
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