促胃泌素釋放肽抗體
規(guī)格：1mg/1ml
英文名： Gastrin Releasing Peptide
別名： Gastrin releasing peptides; BN; Bombesin; GRP 10; GRP; GRP10; Neuromedin C; NeuromedinC; Pre progastrin releasing peptide; preproGRP; proGRP; GRP_HUMAN.
分子量： 3kDa
儲存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Polyclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GRP
交叉反應(yīng)：Human,
促胃泌素釋放肽抗體細(xì)胞定位：分泌型蛋白
產(chǎn)品介紹：background: This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Function:促胃泌素釋放肽抗體 GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear. Subcellular Location: Secreted. Tissue Specificity: Highly expressed both in the lateral nucleus of the amygdala, and in regions sending synaptic projections to the lateral nucleus. Similarity: Belongs to the bombesin/neuromedin-B/ranatensin family. Gene ID: 2922 Database links: Entrez Gene: 2922 Human Entrez Gene: 225642 Mouse Entrez Gene: 171101 Rat Omim: 137260 Human SwissProt: P07492 Human SwissProt: Q8R1I2 Mouse SwissProt促胃泌素釋放肽抗體: P63153 Pig SwissProt: P24393 Rat Unigene: 153444 Human Unigene: 20298 Mouse Unigene: 10930 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GRP廣泛分布于神經(jīng)系統(tǒng)、胃腸道以及正常肺組織中，是神經(jīng)*****。在多種腫瘤中以自分泌方式分泌。能調(diào)節(jié)表皮生長因子，具有多種生物活性。
促胃泌素釋放肽抗體產(chǎn)品應(yīng)用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：腫瘤 神經(jīng)生物學(xué) 生長因子和**
儲存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Rabbit
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