人腦鈉素單克隆抗體
規(guī)格：1mg/1ml
英文名： BNP(H1G3)
別名： BNP 32; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein.
分子量： 14kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Monoclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BNP
交叉反應(yīng)：Human,
人腦鈉素單克隆抗體細(xì)胞定位：
產(chǎn)品介紹：background: Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. 人腦鈉素單克隆抗體This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. 人腦鈉素單克隆抗體Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 腦鈉素主要是心臟**，心臟作為***器官釋放腦鈉素，調(diào)解體液及電解質(zhì)內(nèi)環(huán)境的恒定性。 B型利鈉肽（鈉尿肽）（B－typenatriureticpeptide，BNP），又稱腦鈉素或腦鈉肽，因其有排鈉**、內(nèi)皮非依賴性的血管平滑肌作用而具有降壓、抗心肌纖維化、影響神經(jīng)***系統(tǒng)等功效。 近來(lái)發(fā)現(xiàn)BNP在各種心血管**，尤其是心室功能不全、急性心肌梗死（ami）、高血壓等**的診斷、**及預(yù)后等方面有重要意義，已引起臨床工作者的高度重視。
人腦鈉素單克隆抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：心血管 **學(xué)
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Mouse
外觀： Lyophilized or Liquid
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