轉(zhuǎn)鐵蛋白單克隆抗體
規(guī)格：1mg/1ml
英文名： Transferrin(1F10)
別名： Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; PRO1557; PRO2086; Serotransferrin precursor; Siderophilin; TF; Transferin; Transferrin.
分子量： 77kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Monoclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：Full length native Transferrin protein purified from human p
交叉反應(yīng)：Human,
轉(zhuǎn)鐵蛋白單克隆抗體細(xì)胞定位：
產(chǎn)品介紹：background: This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]. Function: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation 轉(zhuǎn)鐵蛋白單克隆抗體to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Subunit: Monomer. Subcellular Location: Secreted. Tissue Specificity: Expressed by the liver and secreted in plasma. DISEASE: Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Similarity: Belongs to the transferrin family. Contains 2 transferrin-like domains. Gene ID: 7018 Database links: Entrez Gene: 轉(zhuǎn)鐵蛋白單克隆抗體7018 Human Entrez Gene: 22041 Mouse Entrez Gene: 24825 Rat Omim: 190000 Human SwissProt: P02787 Human SwissProt: Q921I1 Mouse SwissProt: P12346 Rat Unigene: 518267 Human Unigene: 37214 Mouse Unigene: 91296 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
轉(zhuǎn)鐵蛋白單克隆抗體產(chǎn)品應(yīng)用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：腫瘤 細(xì)胞生物 **學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Mouse
外觀： Lyophilized or Liquid
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