甲胎蛋白單克隆抗體
規(guī)格：1mg/1ml
英文名： AFP(A2)
別名： Alpha Fetoprotein; AFP; alpha 1 fetoprotein; alpha fetoglobulin; alpha Fetoprotein; Alpha fetoprotein precursor; FETA; HPAFP.
分子量： 65kDa
儲存液：0.01M PBS(pH7.4) with 0.03% Proclin300.
克隆類型：Monoclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：Full length plasma AFP protein
交叉反應(yīng)：Human,
甲胎蛋白單克隆抗體細胞定位：分泌型蛋白
產(chǎn)品介紹：background: Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in *****s is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to甲胎蛋白單克隆抗體 screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries. Subunit: Dimeric and trimeric forms have been found in addition to the monomeric form. Subcellular Location: Secreted. Tissue Specificity: Plasma. Synthesized by the fetal liver and yolk sac. Similarity:甲胎蛋白單克隆抗體 Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains. Gene ID: 174 Database links: Entrez Gene: 174 Human Omim: 104150 Human SwissProt: P02771 Human Unigene: 518808 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. AFP是由胚胎卵黃囊細胞，胚胎肝細胞和胎兒腸道細胞合成的一種糖蛋白。主要用于原發(fā)性或轉(zhuǎn)移性肝細胞癌、肝樣胃癌和性腺或性腺外某些生殖細胞腫瘤(如內(nèi)胚竇瘤)的診斷和鑒別診斷。 AFP敏感度較低，特異性強，大約60%左右的肝細胞肝癌陽性，在低分化腫瘤中常呈陽性表達。 該抗體與bsm-1622M（檢測）（Anti-Alpha Fetoprotein）配對使用；主要用于ELISA試劑盒，膠體金試劑條制備生產(chǎn)都很好。大量訂購可來電商議。
甲胎蛋白單克隆抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：腫瘤
儲存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源： Mouse
外觀： Lyophilized or Liquid
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