野生型P53誘導(dǎo)基因1單克隆抗體
規(guī)格：1mg/1ml
英文名： PAG608 (3E4)
別名： p53 activated gene 608; PAG608; FLJ12296; MGC10613; OTTHUMP; OTTHUMP; p53-activated gene 608 protein; PAG 608; WIG 1; Zinc finger matrin-type protein 3; Zinc finger protein WIG-1
分子量： 32kDa
儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型：Monoclonal
亞型：IgG
純化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human WIG-1/PA
交叉反應(yīng)：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Guinea Pig,
野生型P53誘導(dǎo)基因1單克隆抗體細(xì)胞定位：細(xì)胞核
產(chǎn)品介紹：background: This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms 野生型P53誘導(dǎo)基因1單克隆抗體differing in only one amino acid. Subunit: Interacts with dsRNA. Subcellular Location: Nucleus. Nucleus, nucleolus. Tissue Specificity: Highly expressed in ***** brain, and moderately in ***** kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine. Similarity: Contains 3 matrin-type zinc fingers. Gene ID: 64393 Database links: Entrez Gene: 64393 Human Entrez Gene: 22401 Mouse Entrez Gene: 64394 Rat Omim: 606452 Human SwissProt: Q9HA38 Human SwissProt: O54836 Mouse SwissProt: O08781 Rat Unigene: 野生型P53誘導(dǎo)基因1單克隆抗體371609 Human Unigene: 35705 Mo Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
野生型P53誘導(dǎo)基因1單克隆抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域：腫瘤 細(xì)胞生物 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 細(xì)胞周期蛋白
儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來(lái)源： Mouse
外觀： Lyophilized or Liquid
- 溫馨提示：為規(guī)避購(gòu)買風(fēng)險(xiǎn)，建議您在購(gòu)買前務(wù)必確認(rèn)供應(yīng)商資質(zhì)與產(chǎn)品質(zhì)量。
- 免責(zé)申明：以上內(nèi)容為注冊(cè)會(huì)員自行發(fā)布，若信息的真實(shí)性、合法性存在爭(zhēng)議，平臺(tái)將會(huì)監(jiān)督協(xié)助處理，歡迎舉報(bào)