白細(xì)胞介素-2單克隆抗體

規(guī)格：1mg/1ml

儲(chǔ)存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆類型：Monoclonal

亞型：IgG

純化方法：affinity purified by Protein G

**原：KLH conjugated synthetic peptide derived from human IL-2

交叉反應(yīng)：Human,

白細(xì)胞介素-2單克隆抗體細(xì)胞定位：分泌型蛋白

產(chǎn)品介紹：background: The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential 白細(xì)胞介素-2單克隆抗體role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008] Function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Subcellular Location: Secreted. DISEASE: Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Similarity: Belongs to the IL-2 family. Gene ID: 3558 Database links: Entrez Gene: 3558 Human Entrez Gene: 16183 Mouse Entrez 白細(xì)胞介素-2單克隆抗體Gene: 116562 Rat Omim: 147680 Human SwissProt: P60568 Human SwissProt: P04351 Mouse SwissProt: P17108 Rat Unigene: 89679 Human Unigene: 14190 Mouse Unigene: 9871 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. IL-2作為一種T細(xì)胞生長(zhǎng)因子在**應(yīng)答及其調(diào)節(jié)中起重要作用,IL-2的拮抗劑可用于同種移植排斥、T細(xì)胞性白血病以及某些自身**性**的**.胞內(nèi)IL-2的水平是反映Th1 /Th2型細(xì)胞平衡狀態(tài)的一個(gè)有用指標(biāo),血清IL-2的水平異常增高與某些**密切相關(guān)

白細(xì)胞介素-2單克隆抗體產(chǎn)品應(yīng)用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究領(lǐng)域：**學(xué)  糖蛋白  

儲(chǔ)存條件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

來(lái)源： Mouse

外觀： Lyophilized or Liquid