Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP.

Applications:

WB

Name of antibody:

PTPRC(Phospho-Ser1007)

Immunogen:

Peptide sequence around phosphorylation site of serine 1007 (D-D-S(p)-D-S) derived from Human CD45.

Full name:

protein tyrosine phosphatase, receptor type, C

Synonyms：

LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180

SwissProt:

P08575

WB Predicted band size:

147 kDa

WB Positive control:

Hela cells lysates treated with TNF

WB Recommended dilution:

500-1000