Background:

Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Applications:

WB

Name of antibody:

GSS

Immunogen:

Fusion protein of human GSS

Full name:

glutathione synthetase

Synonyms：

GSS; GSHS; MGC14098

SwissProt:

P48637

WB Predicted band size:

52 kDa

WB Positive control:

293T, HeLa and HT-1080 cells

WB Recommended dilution:

500-2000