環(huán)指蛋白43抗體
規(guī)格:1mg/1ml
英文名: RNF43
別名: RNF124; Ring finger protein 43; URCC; RNF43_HUMAN; E3 ubiquitin-protein ligase RNF43; RING finger protein 43.
分子量: 83kDa
儲存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆類型:Polyclonal
亞型:IgG
純化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RNF43
交叉反應(yīng):Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
細胞定位:細胞核 細胞漿 細胞膜
環(huán)指蛋白43抗體產(chǎn)品介紹:background: RNF43 is a probable E3 ubiquitin-protein ligase that promotes cell growth and is upregulated in colon cancer. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Function: Probable E3 ubiquitin-protein ligase. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Subunit: Interacts with AKAP8L, NONO and SFPQ. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). 環(huán)指蛋白43抗體Nucleus envelope. Tissue Specificity: Expressed in fetal kidney, fetal lung, in colon cancer tissues, hepatocellular carcinomas and lung adenocarcinomas. Overexpressed in colorectal cancer cell lines. Similarity: Contains 1 RING-type zinc finger. Gene ID: 54894 Database links: Entrez Gene: 54894 Human Entrez Gene: 207742 Mouse Entrez Gene: 303412 Rat Omim: 612482 Human SwissProt: Q68DV7 Human SwissProt:環(huán)指蛋白43抗體 Q5NCP0 Mouse Unigene: 584916 Human Unigene: 440230 Mouse Unigene: 214174 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
環(huán)指蛋白43抗體產(chǎn)品應(yīng)用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究領(lǐng)域:腫瘤 細胞生物 腫瘤細胞生物標(biāo)志物
儲存條件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
來源: Rabbit
外觀: Lyophilized or Liquid
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